CSI 2025: A Year of Growth, Impact, and Innovation

Browse our top comparator medicines with CoA, including leading oncology and biosimilar products, available through qualified global manufacturers and suppliers. Upcoming Events Stay up to date with where you can meet the CSI team next. Here you’ll find the conferences and industry events we’re attending, with dates, locations, and booth or session details. If you’re a sponsor, CRO, or CMO, book a meeting to discuss comparator sourcing, global clinical trial supply, and end-to-end logistics. Check back for updates or use the links below to schedule time with us. Schedule a meeting for our next event 11 December 2025 Test conference Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut Get Started 19 December 2025 Expopharm Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam, quis nostrud exercitation ullamco laboris nisi ut aliquip ex ea commodo consequat. Get Started 11 November 2025 CTS Conference Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam, quis nostrud exercitation ullamco laboris nisi ut aliquip ex ea commodo consequat. Get Started

Browse our top comparator medicines with CoA, including leading oncology and biosimilar products, available through qualified global manufacturers and suppliers. Upcoming Events Stay up to date with where you can meet the CSI team next. Here you’ll find the conferences and industry events we’re attending, with dates, locations, and booth or session details. If you’re a sponsor, CRO, or CMO, book a meeting to discuss comparator sourcing, global clinical trial supply, and end-to-end logistics. Check back for updates or use the links below to schedule time with us. Schedule a meeting for our next event 11 December 2025 Test conference Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut Book a meeting 19 December 2025 Expopharm Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam, quis nostrud exercitation ullamco laboris nisi ut aliquip ex ea commodo consequat. Book a meeting 11 November 2025 CTS Conference Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam, quis nostrud exercitation ullamco laboris nisi ut aliquip ex ea commodo consequat. Book a meeting

Get answers to frequently asked questions about Clinical Services International (CSI), including our pharmaceutical sourcing solutions, supply chain services, and how we streamline clinical trial management for biotech and pharma companies. Frequently Asked Questions Welcome to our FAQs page. Here you'll find answers to the most common questions about our services, capabilities and how we support clinical trials globally. If you can’t find what you're looking for, feel free to contact us . What services does CSI provide? CSI provides all the services required for clinical trial supply including comparator and ancillary sourcing, forecasting, regulatory support, QP services, temperature-controlled storage and distribution, direct-to-patient distribution, packing and labelling services and supply chain optimization tailored to each trial’s needs. What types of studies do you support? We support from Phase I to Phase III and commercialisation studies across all therapeutic areas, with extensive expertise in Oncology. We handle single country to complex multi-country global studies (our largest study including 45 countries), with expertise in projects requiring Certificates of Analysis (CoAs) and regulatory documentation. What makes CSI different from other clinical supply providers? CSI offers a unique combination of: Direct accounts with all major manufacturers, branded and generic An entirely scientific team with extensive experience in drug development Truly global reach with offices and warehouses in UK, Germany and USA Recognition as a Women-Owned Organization and EcoVadis Platinum certified company, emphasizing diversity and sustainability. Proven ability to shorten study approval times and reduce lead times through strategic sourcing. Where do you source your products from? We source directly from global pharmaceutical manufacturers, wholesalers and authorized distributors. This ensures product authenticity, traceability and full chain of custody. Can CSI provide products that require Certificates of Analysis (CoA)? Yes. We are highly experienced in supplying products with CoAs and can accommodate even the most complex quality assurance and documentation requirements. What geographic regions do you serve? CSI serves clients worldwide, with strength in multi-country clinical trials across Europe, North America, Asia-Pacific, and Latin America; the most complex study included 45 countries. Our logistics partners are validated to meet international GDP (Good Distribution Practice) standards. What types of medicines does CSI source? CSI sources a wide range of commercial medicines, including: Branded pharmaceuticals Generic equivalents Biologics Biosimilars Cold chain and temperature-sensitive products High-value specialty drugs We support sourcing across all therapeutic areas and have direct access to global manufacturers, ensuring authenticity, compliance, and full documentation. How do you ensure product integrity during shipping? All shipments are managed using validated, temperature-controlled packaging and monitored with real-time data loggers. We adhere strictly to GDP guidelines and provide full traceability and documentation. What accreditations or certifications does CSI hold? CSI is EcoVadis Platinum certified, highlighting our commitment to ethical sourcing, sustainability and corporate responsibility. We are also a recognized Women-Owned Business and comply with all relevant GDP and GMP standards. How can I request a quote or consultation? You can easily request a quote or schedule a meeting by submitting a request through our website, or by emailing us at info@csint.com. A member of our team will respond promptly. Which therapeutic areas does CSI specialize in? CSI supports clinical trials across all major therapeutic areas, including but not limited to: Oncology Immunology Infectious Diseases Neurology Cardiovascular Endocrinology (e.g., diabetes) Rare and Orphan Diseases Our experience spans both common and complex indications, including trials requiring highly specialized or limited-availability medications. Can you source multiple batches of the same product? Clinical Services International has extensive expertise doing batch hunting and providing multiple batches of the same products usually used for analytical purposes. You can refer to our case study here: Who are CSI’s clients? We are proud suppliers to leading Pharmaceutical and Biotechnology companies, as well as Contract Research Organizations (CROs) and Contract Development and Manufacturing Organizations (CDMOs) around the world. Still have questions? We're here to help. Contact CS I or call us directly at +44 (0)203954 0518 , +49 (0)30 2843 0782 or +1 (267) 267 3993 .

Browse our top comparator medicines with CoA, including leading oncology and biosimilar products, available through qualified global manufacturers and suppliers. Top Product List with CoA Working with CSI will streamline your clinical trial supply chain and ensure high-quality comparator drugs Abraxane nab-paclitaxel Avastin bevacizumab Bavencio avelumab Caelyx liposomal doxorubicin Caprelsa vanvdetanib Darzalex daratumumab Dupixent dupilumab Eylea aflibercept Herceptin trastuzmab Humira/Amgevita/Yuflyma adalimumab Ibrance palbociclib Jakavi/Jakafi ruxolitnib Keytruda pembrolizumab Lucentis ranibizumab Mabthera/Truxima rituximab Mounjaro/Zepbound tirzepatide Ocrevus ocrelizumab Ozempic semaglutide Ozempic/Wegovy semaglutide Polivy polatuzumab vedotin Rybelsus semaglutide Stivarga regorafenib Talzenna talazoparib Venclyxto venetoclax Yervoy ipilimumab Zytiga abiraterone acetate Brand Name Scientific Name Frequently Supplied Comparator Medicines Partnering with CSI streamlines your clinical trial supply chain, ensuring the timely and cost-effective sourcing of high-quality comparator drugs. With our scientific expertise, we offer guidance on new investigative medicines while leveraging our global reach and unwavering focus on quality. CSI specializes in supplying oncology products for global clinical trials, having successfully supported over 1000 trials. Our offerings range from generics to advanced cold-chain biologics. We also have extensive experience in providing biosimilar medicines for diverse clinical trials, expertly navigating complex regulatory requirements worldwide. Our strong relationships with over 200 leading manufacturers and a global network of trusted suppliers position CSI as your ideal partner for biosimilar and oncology product needs.

CSI delivers bespoke global clinical trial supply chain solutions, from sourcing medicines and ancillaries to storage, distribution and project management. We provide world-leading, bespoke clinical trial supply chain solutions Clinical Services International (CSI) delivers best-in-class clinical trial supply solutions by developing tailor-made sourcing strategies for our partners, carrying out proactive project management, and ensuring the timely and efficient distribution of medicines and medical devices. When procuring medicines and ancillaries for our partners’ clinical trials, we know that delivering the right sourcing strategy can yield massive savings. Our unparalleled access to products manufactured around the world and our logistical capabilities mean we have never failed to deliver to a study. Our Services Medicines and Ancillaries Storage and Distribution Project Management Medicines and Ancillaries Storage and Distribution Project Management Medicines and Ancillaries Comparator Drug Sourcing At CSI, we take a scientific approach to comparator sourcing based on our 25 years of experience in the clinical trial supply industry. Comparators are on the critical path of almost all clinical studies but are increasingly expensive and hard to find. We pride ourselves on finding the unfindable, sourcing comparator drugs that allow clinical trials to run on time and provide better patient outcomes. The clinical supply partner of choice Pharmaceutical companies , biotechnology companies and Clinical Research Organisations (CROs) must have robust comparator sourcing strategies in place to ensure that comparator drugs are supplied to all clinical trial sites at a competitive price and without disruption. CSI has supplied medicines to over 1,000 clinical trials across lifecycle phases 1 to 4, supporting our partners with even the most complex and challenging requirements. We understand that every clinical study is different and requires a customised approach. With the experience to take on even the most complex adaptive trials, we know how to reduce complexity and drive value, delivering sourcing strategies to improve the speed and agility of your study. CSI delivers results with: A comprehensive understanding of clinical trial requirements and protocols Fully bespoke sourcing solutions, whether country-specific, global or hybrid A global network of qualified suppliers, manufacturers and wholesalers A wide range of suppliers to minimise risks and enable sourcing of specific batches Full documentation, client support and supply chain transparency CSI’s six drivers of effective comparator sourcing Understanding the science behind a clinical trial informs CSI’s efficient supply strategies Protocol interpretation Protocol interpretation Product access Product access Supply continuity Supply continuity Cost control Cost control Speed Speed Supporting documents Supporting documents graph Our most frequently supplied comparator medicines Abraxane nab-paclitaxel Oncology Avastin bevacizumab Oncology Bavencio avelumab Oncology Brand Name Sciticifc Indication Eylea aflibercept Ophthalmology Humira adalimumab Arthritis Ibrance palbociclib Oncology Jakavi ruxolitinib Oncology Keytruda pembrolizumab Oncology Lucentis ranibizumab Ophthalmology Mabthera rituximab Oncology Opdivo nivolumab Oncology Roactemra tocilizumab Arthritis Stivarga regorafenib Oncology Talzenna talazoparib Oncology Tecentriq atezolizumab Oncology Yervoy ipilimumab Oncology Branded Name Scientific Name Indication Overcoming the challenges of comparator drug sourcing The sourcing of comparator drugs and non-investigational medicinal products (NMPs) has become increasingly critical as most drugs are now tested against the standard of existing care. Despite market growth and development, it is becoming more difficult to guarantee the timely availability of comparator drugs due to many of the products being biologic medicines , which are difficult to produce and distribute. Working with CSI will streamline your clinical trial supply chain and ensure high-quality comparator drugs are sourced in a timely and cost-effective manner. Our scientific expertise means we can advise on new investigative drugs and, with our global reach and emphasis on quality , you can always rely on us to deliver. Case Studies Oncology Products Biosimilars Oncology Products CSI specialises in supplying oncology products to global clinical trials. We have successfully delivered oncology products to more than 1000 studies, from generics to the most sophisticated cold chain biologics Discover more Biosimilars CSI has extensive experience of supplying biosimilar medicines to a wide range of clinical trials, including the navigation of strict government regulations around the world. Our strong relationships with leading manufacturers and our global network of trusted suppliers make us the ideal supply partner for biosimilars. Discover more Comedications The standard of care for many indications, especially in oncology, is now a combination of drugs that together provide maximum efficacy. Comedications may be used to alleviate side effects or to improve the potency of the treatment. Comedications are common in cancer treatment because of the multitude of biological mechanisms at play in disease progression. Combination therapies play a crucial role in the comprehensive care of patients, from managing risks to creating synergies that give the gold-standard of treatment. Critically, for clinical trials, the increasing prevalence of combination therapies being used as comparators means more complexity and greater risk from delays, drug shortages, disruptions and compromised supply chains. Securing multiple products on time, and in the right condition, is even harder when each requires a different supplier and logistics solution. CSI has the expertise and experience to help our partners to overcome these challenges. Our scientifically-minded team has the knowledge to advise on the optimal sourcing strategy for all comedications and combination therapies that might be required for any trial, factoring in origin of supply, price, logistics and shipment timing. Rescue Studies We apply our same expertise, global footprint and operational excellence in service of global studies that may need rescuing, whether this relates to issues of procurement, sourcing, resource, compliance, quality or timelines. With CSI’s decades of experience in the clinical trial supply industry and dedicated client relationship managers, we are here to help you get your study back on track. CSI has sourced rescue medications for a range of global studies, including the supply of infliximab, salbutamol, ruxolitinib and mycophenolate motefil. Case Study Direct-to-patient services for decentralized trials Streamline your supply chain by combining Direct-to-Patient and traditional clinical trial services Direct-to-Patient (DTP) services enable decentralized clinical trials by delivering investigational products directly to patients’ homes. CSI offers four flexible DTP models. Clinical Site-to-Patient, Depot-to-Patient, Pharmacy-to-Patient, and Hybrid to ensure temperature control, compliance, and patient convenience. These models help accelerate timelines, improve trial quality, and support enrollment in studies involving rare diseases or dispersed patient populations. Sending IMPs from a site depot/CP to a home nurse, who then delivers to patients at the time of their home visit ----- H2---- Hybrid Option Central pharmacy to patient is best suited for temperature control / minimize deviations ----- H2---- Pharmacy to Patient GMP depot to patient – Best suited for temperature control / minimize deviations ----- H2---- Depot-to-Patient The IMP is shipped directly from the main or sub depot to the patient home. Nurse services may be added ----- H2---- Clinical Site-to-Patient Considerations about DTP Key benefits and challenges of adopting Direct-to-Patient models Ideal for trials involving a rare disease, orphan indication, or dispersed patient population Decrease timelines Improve quality Reduce costs Enroll and retain more patients Process complexity Ensuring GMP compliance CSI therapeutic areas Oncology Cardiovascular Respiratory Neurology Infectious Diseases Immunology Autoimmune Endocrinology Metabolic Disorders Hematology Gastroenterology Dermatology Ophthalmology Nephrology Urology Orthopedics Rare Diseases Vaccines Medical Devices and Ancillaries As well as medications, clinical trials often require a wide variety of ancillary supplies, including medical devices, technological equipment, disposable products and print materials. At CSI, we apply our sourcing capabilities, logistical expertise and robust quality standards to ensure that all essential supplies reach trial sites in a reliable and cost-effective manner, no matter their location. Leveraging our partnerships with leading manufacturers, we can offer significant cost savings on medical devices and ancillaries required to support our partners’ clinical trials, including: Up to 60% on initial shipments Up to 40% on resupply shipments Up to 60% on broker fees (customs clearance) Case Study CSI’s ancillary services include the rapid delivery of Medical equipment Electrocardiogram (ECG) tests Spirometers Weighing scales Blood pressure monitors Infusion pumps Cooled or uncooled centrifuges Refrigerators Freezers with temperatures ranging from -20°C to -80°C Technological equipment eDiaries Mobile devices Laptops Printers Pill splitters Print materials Investigator site files Pharmacy binders Patient recruitment material Download our Ancillaires brochure Medical equipment Technological equipment Print materials START Electrocardiogram (ECG) tests Spirometers Weighing scales Blood pressure monitors Infusion pumps Cooled or uncooled centrifuges Refrigerators Visit our Sustainability page eDiaries Mobile devices Laptops Printers Pill splitters Investigator site files Pharmacy binders Patient recruitment material Storage and Distribution CSI has delivered comparator medicines, medical devices and ancillaries to thousands of clinical trials around the world. Our extensive experience and global reach mean we can advise our partners on the best strategy for supplying any study – whether this involves direct-to-site shipments, local or regional depots, or hybrid solutions – to ensure the necessary products arrive on time, within budget, and at the required location. We understand the challenges of managing a complex clinical trial supply chain and can deliver to your site, warehouse or packaging agent. CSI’s integrated, end-to-end distribution solutions allow our partners to maintain focus on the drug development process, keeping studies flexible, agile and on schedule. Delivering for our partners Strategically positioned global depot network International clinical trials require global facilities in strategic regions combined with local insight and experience of a variety of regulatory requirements. CSI’s global depot network spans 60 countries and six continents, allowing us to identify the most cost-effective solutions for any trial supply, while maintaining flexibility and allowing for contingencies. - Our Global Reach Warehouses and offices Our network extends to 60 countries on six continents Specialized Cold-Chain Logistics CSI provides end-to-end cold and ultra-cold chain logistics for temperature-sensitive clinical trial supplies. We plan, source, pack, store and deliver medicines globally at 2–8°C , –20°C , and –80°C , using GDP-compliant processes, validated packaging and qualified couriers Our global network of qualified logistics providers ensure full product integrity through real-time temperature monitoring and data logging. All shipments are supported by risk assessments, route mapping and contingency planning to prevent temperature excursions. CSI’s expertise covers high-value and short-shelf-life products, including biologics and oncology therapies. We manage site-specific requirements, customs clearance and product handling across multiple regulatory regions. Our cold-chain solutions are built to support global Phase I–III trials with scalability, reliability and full regulatory compliance. Global expertise with unrivalled global knowledge CSI is headquartered in London and has offices in the United Kingdom, the United States, Germany, and China. Delivering clinical trial supplies to some of the world’s most difficult-to-reach markets, our experienced and knowledgeable teams have comprehensive knowledge of import and export logistics, as well as the movement of investigational medicinal products (IMPs) across all global markets. Our international reach ensures we can source the clinical supplies needed for even the most complex trials and deliver them on time and within budget. Locations We overcome distribution challenges CSI’s flexible clinical trial supply strategies ensure we can overcome any distribution challenges that might affect the outcome of our partners’ clinical trials, including: Breakdowns in the logistical supply chain Slow-paced patient recruitment Resource availability Fluctuation in demand Expiring batches Our clinical distribution strategy covers logistical planning, imports, exports and inventory shelf-life control, and our centralised compliance team oversees the entire study. This reduces vendor complexity and ensures clinical supplies are delivered within the agreed timeframe. Project Management We value clear communication Throughout the clinical trial supply process, CSI implements study-specific systems to update and communicate clearly and regularly with our partners and supply network, so all parties are kept informed of the status of clinical trial supplies. To aid transparency and efficiency, each of our partners is assigned a dedicated project manager from CSI who is responsible for overseeing the project from the proposal stage to delivery. Direct-to-site delivery For open label studies, CSI can deliver directly to sites in a fast, reliable and cost-effective manner. We work closely with project managers, assisting with trial forecasts to ensure that medication is available at all sites when needed. Our flexible and adaptive solutions help our partners to save resources and facilitate effective patient recruitment and retention. Controlled transport and storage CSI is licensed by the Medicines and Healthcare products Regulatory Agency (MHRA) and the Berlin State Office for Health and Social Affairs (LAGeSo). We are experts in cold chain biologic, temperature-controlled and ambient product delivery, and our quality management system ensures full compliance with regulatory requirements around the world. All our depots are audited to ensure the highest standards of Good Manufacturing Practice (GMP), while our end-to-end transport and storage services are monitored at every stage of the distribution process. Quality Secure shipment tracking All CSI warehouse and shipment activities are tracked using GPS and our specialised inventory system, so we are always in control of our stock levels and can guarantee full traceability from pick-up until delivery. We provide partners with full visibility throughout the logistical process, and our tracking system efficiently flags low stock levels and impending expiry dates. We can also provide, as required, customised inventory reports that document: Materials Tracking numbers Shipment and receipt date Serial numbers Batch numbers Temperature records Materials Tracking numbers Shipment and receipt date Serial numbers Batch numbers Temperature records Returns, reconciliation and destruction CSI also handles returns and destruction at the site level. We can return damaged, expired or unused medications to our warehouses for final reconciliation destruction. We produce comprehensive final reports as part of the close-out document of the study. Contact Us Project Management CSI has over 150 years of experience in developing effective comparator sourcing strategies. We use our expertise to successfully plan and manage the entire sourcing supply chain, helping to simplify the supply process, minimise risk and maximise cost savings for our partners. With our service-orientated approach, our partners benefit from a dedicated relationship person and ongoing support and problem solving at every stage of a project. There are many moving parts and unpredictable factors at play in clinical supply chains. With CSI’s specialist project management and logistical expertise, we understand the complexities involved in planning and managing clinical trial supplies and strive to mitigate any risks that might prevent our pharmaceutical, biotechnology and CRO partners from operating at maximum efficiency. We have never failed to deliver to a study Protocol and market analysis “A scientific approach to clinical trial supply” An effective clinical supply management strategy begins with the comprehensive understanding of a trial protocol. This is where CSI’s 150 years of scientific expertise sets us apart from other clinical trial supply companies, allowing us to provide the best possible advice on the most efficient and cost-effective sourcing strategy for any study. Analysing trial-specific factors such as the required medications, ancillaries, quantities, locations, documentation, timeframes and the availability of generics, allows CSI to present an optimised local, central, market, manufacturer, wholesaler or hybrid sourcing strategy. With experience of shipping to even the most remote countries around the world, we offer expert regulatory guidance, can anticipate global supply challenges, and develop custom supply solutions for our partners. Case Study Supply planning and risk management An effective comparator sourcing strategy requires robust forecasting to maximise supply chain efficiency and minimise potential costs for all parties. Thorough forecasting involves identifying the potential risks that might arise at each phase of a trial – including fast or slow patient recruitment; availability, expiry and batch requirements of a medication; potential drug shortages or fluctuations in global market price and demand – and the impact these might have on the clinical supply chain, before ensuring that necessary contingency measures are in place to protect budgets, timelines and, ultimately, trial data. CSI’s six steps for effective risk management Identify Evaluate Control Communicate Review Report CSI carries out comprehensive scenario planning from the protocol analysis stage onwards. Once a clinical trial is underway, we regularly review forecasted supply requirements against actual drug use to minimise wastage and unnecessary costs. We can also pool inventories for study programmes to reduce waste and to save money for our partners. CSI reduces complexity and adds value by: Sending IMPs from a site depot/CP to a home nurse, who then delivers to patients at the time of their home visit ----- H2---- Hybrid Option Central pharmacy to patient is best suited for temperature control / minimize deviations ----- H2---- Pharmacy to Patient GMP depot to patient – Best suited for temperature control / minimize deviations ----- H2---- Depot-to-Patient The IMP is shipped directly from the main or sub depot to the patient home. Nurse services may be added ----- H2---- Clinical Site-to-Patient Qualified Person and regulatory services All Investigational Medicinal Products (IMPs) must be certified by a Qualified Person (QP) prior to release for use in a clinical trial. CSI’s respected and well-established quality department has in-depth experience across a wide range of product types and dosage forms, and ensures regulatory compliance across all of our international operations. Sourcing and distributing medicines and medical devices globally requires extensive knowledge of regional regulations that differ from country to country. CSI’s regulatory and quality assurance experts have longstanding relationships with MHRA and EMA and can provide advice and solutions for our partners’ clinical trial supply needs. Since documentation is often necessary for import and export purposes, all our products are delivered certified. By conducting thorough and proactive quality control checks throughout the entire supply chain, CSI identifies and mitigates any quality issues before they come to fruition, while the depth of our regulatory knowledge allows us to foresee potential roadblocks in the supply chain so we can resolve issues in a timely and efficient manner. Visit our Quality page Contact us Get in touch with a member of our experienced team today to discuss your clinical trial supply requirements Company type Submit

Discover how CSI is making a difference through charity and philanthropy, committed to positively impacting communities and supporting meaningful causes globally. CSI’s Commitment to Giving Back At CSI, we believe in giving back to our communities. Our charitable initiatives span a wide range of causes, reflecting our commitment to making a positive impact both locally and globally. As part of our dedication to community support, CSI provides all employees with one paid day each year to participate in charity work of their choice. In addition, we proudly contribute to the following organizations and initiatives: Charity & Philanthropy Cambridge MBA Scholarship (UK) Supporting the next generation of leaders in Science CSI is proud to have set up The Vanessa Dekou Scholarship for Scientists to contribute to the education of the next generation of leaders in life sciences. The Vanessa Dekou Scholarship for Scientists will help finance a Cambridge MBA education for candidates with advanced degrees in scientific fields such as biological sciences, chemistry and physics. CSI is a great believer that education creates opportunities, so the scholarship aims to assist scientists advance their business understanding and credentials in order to become part of the next generation of leaders and contribute to scientific advancement. In addition, Vanessa, Founder and Managing Director of CSI, is a member of the Advisory Board of Cambridge Judge Business School. When I arrived at the UK in September 1991, as an undergraduate, I had big dreams about my future. I educated myself to PhD/MBA level and through my education, perseverance and incredible hard work I managed to build CSI from scratch; to contribute to advances in healthcare and create employment and prosperity. I am thrilled and humbled that through Cambridge Judge Business School I am in the fortunate position to give back to our society and inspire other scientists to innovate and progress. Vanessa Dekou - We are very grateful to Vanessa Dekou for establishing this wonderful scholarship in her name to help fund a Cambridge MBA education for students with a scientific background. Cambridge Judge is proud to integrate vital areas such as healthcare, climate change and technology into our Business School curriculum and activities, so this scholarship will help us to attract people with diverse backgrounds in science who can use their Cambridge Judge experience to advance scientific knowledge. Gishan Dissanaike - Dean of Cambridge Judge Business School Enhancing healthcare for local communities Enhancing healthcare for local communities We donate generously each year through funding and support to CW+, the official charity of Chelsea and Westminster Hospital NHS Foundation Trust, which encompasses Chelsea and Westminster Hospital, West Middlesex University Hospital and all our community-based services and serves a population of more than 1.5 million people. Our contribution aims to enhance ongoing delivery of outstanding care to the communities the Trust serves through a plethora of innovative initiatives, pilots of new clinical services and trials of cutting-edge technology, which lead to improved clinical practice and greater understanding of effective treatments. Vanessa, Founder and Managing Director of CSI, is a member of the Innovation Advisory Group of CW+. Queen Mary University of London Digital Environment Research Institute (DERI), PhD Scholarship. CSI is proud to be an industry partner supporting a PhD position at Queen Mary University of London in collaboration with Singer Instruments. This research focuses on uncovering mechanisms of mTOR inhibition resistance through drug repurposing, interactomics, and AI—a vital step in advancing drug discovery and improving treatment outcomes. As part of the UKRI/BBSRC AI for Drug Discovery Programme, this project will contribute to cutting-edge innovation in the pharmaceutical space Ladies Union of Drama (Greece) Empowering women through education and resources. We aspire for our contribution to be community-led and sustainable, to build community capacity and support social welfare, public health and social care. As such, we donate generously each year through funding to community groups and organizations that support diverse and inclusive communities. Our focus during the past year has been the Ladies Union of Drama, Greece, an award-winning small-scale non-profit philanthropic agency with big impact. The purpose of the Ladies Union of Drama is to offer social and humanitarian work in the community of citizens and, especially, of vulnerable social groups. They aim to educate and develop solidarity, combat of gender violence, xenophobia and racism, raise public awareness on issues of equality, equity, human and democratic rights, support of fellow citizens. graph Battersea Foil Promoting sports in youths. Battersea is a small club with good overseas and London connections. The club has a 50:50 male to female ratio, and has a number of fencers on sponsored places, with the club running on a not-for-profit basis. We are proud to financially support and inspire young athletes to start, stay and succeed in fencing. Battersea Foil Website Arcangelo Supporting excellence in music and the arts Arcangelo is an award-winning, internationally-acclaimed period performance ensemble led by its founder and artistic director Jonathan Cohen. A registered charity, receiving no state funding, Arcangelo replies upon the generosity of individuals and companies such as ours, who believe that young musicians should be nurtured and supported to develop their skills and talent. Arcangelo Website Chcepomagam Foundation (Poland) Helping those in need through various social projects. We contributed with several packages of medicines such as nose drops, cough medicine and analgesics to the Chcepomagam Foundation to aid their provision for humanitarian aid in Ukraine. Humanitarian aid has reached several important places in Ukraine including Special Centre for Mother and Child in Drohobych, Mixed Children's Home "Oranta" in Drohobych, Regional Specialist Children's Home in Nadvirnay, Ivano-Frankivsk Special School – Rehabilitation Center in Ivano-Frankivsk. Chcepomagam Foundation Website Queen Mary University of London Digital Environment Research Institute (DERI), PhD Scholarship. CSI is proud to be an industry partner supporting a PhD position at Queen Mary University of London in collaboration with Singer Instruments. This research focuses on uncovering mechanisms of mTOR inhibition resistance through drug repurposing, interactomics, and AI—a vital step in advancing drug discovery and improving treatment outcomes. As part of the UKRI/BBSRC AI for Drug Discovery Programme, this project will contribute to cutting-edge innovation in the pharmaceutical space Project Page In Action Our team actively participates in charitable events. CSI’s UK Marketing Associate Yasmine represented CSI in the 2024 ‘La Montpellier Reine’ race against Breast Cancer. The CSI Team attended the Chelsea and Westminster Hospital NHS Foundation Trust Gala in support of the CW Plus Team Thirty at Thirty appeal at Mansion House. It was an honour to be a part of this charity fundraising event, in aid of our local hospital. New Cancer and Renal Disease centres are underway. At CSI, we strive to create meaningful change, one initiative at a time. Medical equipment Technological equipment Print materials START Electrocardiogram (ECG) tests Spirometers Weighing scales Blood pressure monitors Infusion pumps Cooled or uncooled centrifuges Refrigerators Visit our Sustainability page eDiaries Mobile devices Laptops Printers Pill splitters Investigator site files Pharmacy binders Patient recruitment material

Clinical Services International (CSI) USA Operations delivers expert clinical trial solutions across North America, ensuring efficient supply chain management and streamlined access to comparator medicines. USA Operations Supporting Clinical Trials Across the Americas and Beyond At Clinical Services International (CSI), our USA operations play a vital role in providing global clinical trials with local expertise, regulatory knowledge and logistical capabilities. Our USA base, centered in Horsham, Philadelphia, PA, allows us to support clients in America with exceptional access to manufacturers, a high-performing distribution hub and a deeply experienced project management team. US Warehouse Global Reach, Local Expertise Did you know CSI supports clinical studies in over 60 countries across North America, Europe, Latin America, Asia-Pacific and the Middle East. With our USA presence, we seamlessly integrate sourcing, packaging, labelling and logistics to meet the demands of complex, multinational clinical trials. Our team understands the regulatory frameworks of the FDA, EMA, MHRA and other global health authorities, ensuring a compliant and efficient supply chain across borders. Our Services - Our Global Reach Warehouses and offices Our network extends to 60 countries on six continents What We Do in the USA? Whether you're running a Phase I trial in the USA or managing a global Phase III study, we ensure consistent, secure, and timely delivery of critical clinical supplies. At our state-of-the-art warehouse in Horsham, PA, CSI provides end-to-end services, including: From direct accounts with USA manufacturers and authorized distributors Comparator Sourcing Comparator sourcing Temperature-controlled storage solutions Storage and Distribution Cold-chain logistics In accordance with global regulatory standards Packaging Clinical packaging & labelling With full traceability Warehouses Inventory and expiry management By USA-based experts with global coordination Project Management Project management Across North and Latin America Shipments Direct-to-site and depot shipments Did You Know? CSI has excellent access to markets in APAC and Latin America , thanks to our established global supplier network and regional logistics partnerships. That means we can ship comparator and ancillary supplies directly to your sites, wherever they are, without delay. Why Pharmaceutical and Biotechnology companies choose CSI for their USA Studies Fast turnaround times across the Americas Reliable access to branded and generic medications Fully qualified suppliers and temperature-controlled logistics Regulatory support for import/export and labelling compliance Experienced scientific and project teams with deep therapeutic knowledge US Warehouse – Directions & Location -> Find our CSI US warehouse easily - click the links below to open directions in your preferred navigation app and ensure smooth access to our facility. graph Medical equipment Technological equipment Print materials Electrocardiogram (ECG) tests Spirometers Weighing scales Blood pressure monitors Infusion pumps Cooled or uncooled centrifuges Refrigerators Visit our Sustainability page START eDiaries Mobile devices Laptops Printers Pill splitters Investigator site files Pharmacy binders Patient recruitment material Contact us Get in touch with a member of our experienced team today to discuss your clinical trial supply requirements Company type Submit

Based in the UK, USA, Germany and Israel, CSI brings science to global clinical trial supply, delivering strategy and efficiencies to support your study. The science-based clinical trial supply specialists with a truly global footprint Clinical Services International (CSI) is a global leader in clinical trial supplies. Headquartered in London, we have offices in the United Kingdom, Germany the United States, and China. With an international network of over 200 manufacturers and depots spanning six continents, we have worldwide access and global project management expertise, sourcing medicines from Europe, the United States, Central and South America, and Asia Pacific. With over 150 years of combined experience in intelligent sourcing and clinical trial supply, our team are in an unrivalled position to deliver bespoke strategies and efficient solutions to support any study, even with the most complex requirements. Our fully integrated services reduce timelines and costs, ultimately accelerating drug development. Who We Are APR 2024 What makes us different? We bring a scientific emphasis to all aspects of clinical trial supply. When you partner with CSI, you can trust our science-driven approach, backed by a team with experience in drug development. By leveraging our academic knowledge and in-depth understanding of clinical trial design and protocols, we can confidently provide advice, quality assurance and ensure secure delivery, allowing trials to run on time and provide better patient outcomes. Leadership With over 25 years of experience in clinical trial design and supply, the CSI leadership team’s scientific knowledge is at the heart of all the services we offer. We understand the complexities involved in sourcing the most appropriate medication for your study and pride ourselves on offering tailor-made solutions to even the most complex of trial requirements. Our science-based approach, coupled with our operational expertise and global reach, allows us to efficiently and ethically specify, source and supply comparators and medical devices for any clinical trial. London Managing Director Dr Vanessa Dekou Vanessa started her career as a research associate at Scotland Yard and later joined LGC Group. She subsequently joined IQVIA, where she worked with some of the world’s largest biopharmaceutical and biotech companies to provide innovative solutions. She has extensive experience in drug development from preclinical to registration and commercialisation strategies, and has secured product registration for several orphan and first-in-class drugs. She was also Chief Commercial Officer of a leading technology provider for patient access to clinical trials. Vanessa was Senior Advisor to DiGamma Capital. She is on the Enterprise Advisory Board of CW+ (the charity of Chelsea and Westminster Hospital NHS Foundation Trust), the Board of the Judge Business School at the University of Cambridge, and on the Board of UCL's Global Business School for Health and undertakes extensive charity work. She has a PhD in Cardiovascular Genetics from University College London (UCL), an MBA from the University of Cambridge and a master’s degree in Market Access from the University of Lyon. London Vanessa Dekou Managing Director Vanessa started her career as a research associate at Scotland Yard and later joined LGC Group. Subsequently, she joined IQVIA, where she worked with some of the world’s largest biopharmaceutical and biotech companies to provide innovative solutions. She has extensive experience in drug development from preclinical to registration and commercialisation strategies. She has secured product registration for several orphan and first-in-class drugs. She was also Chief Commercial Officer of a leading technology provider for patient access to clinical trials. Vanessa was Senior Advisor to DiGamma Capital. She is on the Enterprise Advisory Board of CW+ (the charity of Chelsea and Westminster Hospital NHS Foundation Trust), the Board of the Judge Business School, University of Cambridge, and undertakes extensive charity work. She has a PhD in Cardiovascular Genetics from University College London (UCL), an MBA from the University of Cambridge and a master’s degree in Market Access from the University of Lyon. London Maurizio Tassi Finance Director Maurizio has over 30 years’ experience in investment banking. He has interests and expertise in healthcare and a keen eye for early-stage innovative biotech and medtech companies. Maurizio was on the boards of Molmed S.p.A. and Lay Line Genomics. Before joining CSI, he was a financial advisor of San Raffaele Hospital, Milan, and a fund manager of Luxembourg SICAV (Long-Short Strategy European stocks). He started his career as Head of New Issues, Schroders, and subsequently Managing Director, Capital Markets, Citigroup. He is an Honorary Member of the Italian Medical Society of Great Britain. Maurizio earned his BSc in Anthropology from UCL, and his MSc in Economics from the London School of Economics (LSE). Stephan Mütze With more than 20 years experience in the pharmaceutical industry, Stephan heads CSI’s German office, supporting and managing supplies for complex studies across the world. Before Stephan joined CSI, he held various positions in clinical operations and supply chain management for leading companies. With his combined clinical and logistical background, he is adept at consulting and guiding our partners, ensuring their projects have successful and efficient outcomes. His pragmatic and hands-on approach, as well as his deep knowledge of Good Distribution Practice (GDP) and Good Manufacturing Practice (GMP) regulations, are some of his most valued strengths. Director of Project Management Berlin London Director, Comparator Sourcing Chrys Davies Chrys Davies brings over 25 years of experience in the clinical trial supply industry, with expertise spanning from packaging and labelling operations to global supply chain management and comparator drug sourcing. Before joining CSI, Chrys spent more than 15 years as Operations Manager at a leading global CDMO, where she designed and led large-scale clinical packaging and labelling operations supporting complex multinational studies. Her commitment to operational excellence positioned her as a leader in delivering timely supply solutions for global sponsors. Building on that foundation, Chrys advanced to Global Director of Comparator Sourcing within the same organization, a role she held for over 10 years. In this capacity, she oversaw strategic sourcing activities across multiple therapeutic areas, collaborating with major pharmaceutical partners to ensure the reliable procurement and delivery of critical study drugs worldwide. At CSI, Chrys leverages her extensive operational and strategic experience to further enhance CSI’s global sourcing capabilities, driving innovation and efficiency in clinical supply delivery. London Qualified Person (QP) and Pharmacist Steven Girdlestone Steve is a veteran of the pharmaceutical industry, having started his career at Pfizer in research, development and formulation of novel compounds. Subsequently, he worked as Head Pharmacist in some of the largest NHS Trust Hospitals in the UK, where he gained invaluable experience in stock control, manufacturing, clinical trials and validation procedures. Steve has since moved back to the pharmaceutical and manufacturing industry, where he has extensive expertise in all aspects of site quality and regulatory compliance (MHRA and ISO), third-party EUGMP audits, QP product release on MIA (IMP) licence, and acting as a Responsible Person and Quality Controller. Steve is a Member of the Royal Pharmaceutical Society (RPS), Member of the General Pharmaceutical Council (GPhC) and Member of the Joint Pharmaceutical Analysis Group (JPAG). He is a qualified Pharmacist with BPharm (Hons) and has a Diploma in Psychiatric Pharmacy. Andrea is responsible for strategy and business development, driving CSI’s international expansion in the United States and East Asia, and building partnerships with our top clients. He has over 25 years’ professional experience in strategy, business development, corporate finance and investment banking. Andrea has advised corporate clients on a wide range of strategic and transformational projects, including mergers and acquisitions (M&A), partnerships, initial public offerings (IPOs), privatisations and international expansion across a number of sectors and jurisdictions. He has also been involved in start-ups, both as an investor and a founder. Andrea previously worked for JPMorgan Cazenove, McKinsey, and Booz Allen & Hamilton. He is an Honorary Fellow of Bayes Business School, University of London. London Andrea Giochetta Director of Strategy & Business Development With more than 16 years’ experience in the pharmaceutical industry, Stephan heads up our German office, supporting and managing supplies for complex studies across the world. Before Stephan joined CSI, he held various positions in clinical operations and supply chain management for leading companies. With his combined clinical and logistical background, he is adept at consulting and guiding our partners, ensuring their projects have successful and efficient outcomes. His pragmatic and hands-on approach, coupled with his deep knowledge of Good Distribution Practice (GDP) and Good Manufacturing Practice (GMP) regulations, are some of his strengths most valued by our team and our global partners. US City Name Title Our Team Safety & Security I'm a paragraph. Click here to add your own text and edit me. It’s easy. Just click “Edit Text” or double click me to add your own content and make changes to the font. Transparency I'm a paragraph. Click here to add your own text and edit me. It’s easy. Just click “Edit Text” or double click me to add your own content and make changes to the font. Growth & Innovation I'm a paragraph. Click here to add your own text and edit me. It’s easy. Just click “Edit Text” or double click me to add your own content and make changes to the font. Quality Sustainability CSI is EcoVadis certified with a Platinum Award , a globally recognised benchmark for sustainability in the supply chain. We recognise the importance of sustainable and ethical procurement – for our business model, as well as the planet – and aim to set ourselves apart in the clinical trial supply industry as a transparent and adaptive company. We ensure that all our suppliers are audited and qualified against important criteria, such as environmental compliance Visit our Sustainability page What we value - Our Global Reach Warehouses and offices Our network extends to 60 countries on six continents Quality Sourcing and distributing medicines and medical devices around the world requires extensive knowledge of regional regulations that differ from country to country. CSI’s independent and well-established quality department ensures global regulatory compliance across all our processes and safeguards the quality of every product we supply to a clinical trial. Our regulatory and quality assurance experts have longstanding relationships with MHRA and EMA and can provide expert advice and bespoke solutions. We ensure Timeliness of medicine supplies Consistency and reliability of investigational medicines Traceability throughout our supply chain Comprehensive documentation and record-keeping Digitalized Quality Management System (QMS) through Simploud , a leading eQMS platform. We comply with Falsified Medicines Directive (FMD) Good Distribution Practice (GDP) Good Manufacturing Practice (GMP) Good Storage Practice (GSP) Drug Supply Chain Security Act (DSCSA) We offer Country-specific regulatory expertise Highest standards of quality and safety Relationships with regulatory agencies Independent quality department We can provide Certificates of Analysis (CofAs) Batch Release Certificates (BRCs) Statements of Authenticity (SofAs) Visit our Quality page CSI’s science-based approach to clinical trial supply aims to improve the downstream life sciences industry, helping to make new and safe medicines rapidly available to patients ----- H2---- Innovation We work closely with partners and stakeholders who share our values and build lasting relationships with them based on mutual trust and being the best service provider we can be ----- H2---- Collaboration CSI is proud to operate with honesty and transparency, maintaining the highest ethical standards and upholding the regulations and procedures required in all aspects of our business ----- H2---- Integrity We keep up with evolving industry standards in compliance, logistics and supply chain management. Quality is in our DNA and it is aligned with all our strategic objectives ----- H2---- Quality Maurizio Tassi Maurizio has over 30 years of experience in investment banking. He has interests and expertise in healthcare and a keen eye for early-stage innovative biotech and medtech companies. He has been on the boards of Molmed S.p.A. and Lay Line Genomics. Before joining CSI, he was a financial advisor of San Raffaele Hospital, Milan, and a fund manager of Luxembourg SICAV (Long-Short Strategy European stocks). Maurizio started his career as Head of New Issues, Schroders, and subsequently Managing Director, Capital Markets, Citigroup. He is an Honorary Member of the Italian Medical Society of Great Britain. Maurizio earned his BSc in Anthropology from UCL, and his MSc in Economics from the London School of Economics (LSE). Director of Finance and Legal London Careers As a fast-growing, global company, we are always searching for the very best, innovative and scientific talent to join our team. Visit our Careers page Steven Girdlestone Steve is a veteran of the pharmaceutical industry, having started his career at Pfizer in research, development and formulation of novel compounds. Subsequently, he worked as Head Pharmacist in some of the largest NHS Trust Hospitals in the UK, where he gained invaluable experience in stock control, manufacturing, clinical trials and validation procedures. Steve has since moved back to the pharmaceutical and manufacturing industry, where he has extensive expertise in all aspects of site quality and regulatory compliance (MHRA and ISO), third-party EUGMP audits, QP product release on MIA (IMP) licence, and acting as a Responsible Person and Quality Controller. Steve is a Member of the Royal Pharmaceutical Society (RPS), Member of the General Pharmaceutical Council (GPhC) and Member of the Joint Pharmaceutical Analysis Group (JPAG). He is a qualified Pharmacist with BPharm (Hons) and has a Diploma in Psychiatric Pharmacy. Qualified Person (QP) and Pharmacist London Contact us Get in touch with a member of our experienced team today to discuss your clinical trial supply requirements Company type Submit

CSI has extensive experience of supplying biosimilar medicines to a wide range of clinical trials worldwide. We are the ideal supply partner for biosimilars. The ideal supply partner for biologics and biosimilar medicines CSI has extensive experience of supplying biosimilar medicines to a wide range of clinical trials worldwide. We ensure the quality of products sourced globally, supplying the necessary quantity with the longest possible expiry dates and within the required timeframe. Our strong relationships with leading manufacturers around the world and our global network of trusted suppliers make us the ideal supply partner for biosimilars. Biosimilars What sets CSI apart from other suppliers? We provide competitive quotes for medicines and ancillaries and can often guarantee the price of the product for the duration of the study with the manufacturer’s agreement ----- H2---- Competitive product pricing We coordinate imports and exports globally, and have supplied over 1,000 clinical trials around the world, with the most complex so far involving no less than 17 countries ----- H2---- Worldwide distribution capabilities We provide our partners with sourcing options for both biologics and biosimilars after careful evaluation of the study protocol, highlighting areas for consideration and making informed recommendations ----- H2---- Value-based supply solutions We have longstanding relationships with leading manufacturers around the world and can provide fast, reliable and tailored supply solutions for any clinical trial, no matter how complex ----- H2---- Relationships with manufacturers We have an in-depth understanding of the nature of biologic and biosimilar products and can provide the necessary literature and insight to facilitate discussions and targeted decisions ----- H2---- Scientific knowledge and expertise The ideal clinical trial supply partner To navigate the complex clinical trial supply chain involved with biosimilars, you need the right supply partner. CSI can: Purchase directly from innovator companies Secure large quantities to supply global studies and maintain continuity of supply Ensure product pedigree Accommodate batch requirements and longest possible expiry dates Source a product for analytical purposes (e.g. medicines from a specific batch) Supply larger volumes of the required medicine following testing Global supply and regulatory expertise CSI has extensive experience in sourcing medicines for biosimilar studies where the site of production has an impact on the product license. We offer reliable supply services even in countries where there are very strict government regulations in place. Read more about CSI’s expert regulatory advice CSI has depots in 60 countries – the perfect footprint to deliver biosimilars across the globe North America South America EMEA Asia Pacific Canada Guatemala Mexico Panama United States Argentina Brazil Colombia Panama Austria Belgium Poland Croatia Czech Republic Denmark Portugal Estonia Finland France Romania Greece Hungary Ireland Russia Italy Jordan Latvia Lebanon Lithuania Netherlands Norway Oman Poland Portugal Romania Russia Saudi Arabia Serbia Slovakia South Africa Spain Sweden Switzerland Tunisia Turkey United Arab Emirates United Kingdom Australia China India Croatia Malaysia Philippines Singapore South Korea Taiwan Thailand Vietnam - Our Global Reach Warehouses and offices Our network extends to 60 countries on six continents Stability Data Certificates of Analysis (CofAs) Batch Release Certificates (BRCs) Statements of Authenticity (SofAs) Beyond our outstanding access to biosimilar products, we also provide all documentation required to support clinical trials at every phase, including: We ensure that our supply chains are short and transparent, and have extensive expertise in the complexities of cold chain supply, ensuring a continuously temperature-controlled and monitored environment throughout the entire transportation process. Amgevita (adalimumab) Avastin (bevacizumab) Erbitux (cetuximab) Eylea (aflibercept) Darzalex (daratumumab) Herceptin (trastuzumab) Herzuma (trastuzumab) Humira (adalimumab) Imraldi (adalimumab) Jakavi (ruxolitinib) Keytruda (pembrolizumab) Lucentis (ranibizumab) Mabthera (rituximab) Mvasi (bevacizumab) Opdivo (nivolumab) Remsima (infliximab) Stelara (ustekinumab) Tecentriq (atezolizumab) Truxima (rituximab) Yervoy (ipilimumab) Yuflyma (adalimumab) Zarzio (filgrastim) Ziextenzo (pegfilgrastim) Biologics and biosimilars that CSI has experience in supplying globally include: Oncology Products Oncology product sourcing specialists CSI has supplied oncology products to more than 700 studies – from generics to the most sophisticated cold chain biologics. Biologic Number of Studies Phase of Trial Geography Pembrolizumab 50+ 1, 2, 3 Europe, USA Aflibercept 50+ 1, 2, 3 Europe, USA, Latin America Nivolumab 50+ 1, 2, 3 Global Ipilimumab 50+ 1, 2, 3 Global Ruxolitinib 25+ 2, 3 Global What are Biologics and Biosimilars? Biopharmaceuticals have seen significant advances in recent years, particularly with the development of biologics and biosimilars. These innovative therapies have revolutionised the treatment landscape and have become the new standard of care for various conditions such as cancer, auto-immune disorders and genetic diseases, offering enhanced efficacy and reduced side-effects in comparison to traditional small molecule drugs. A biosimilar is a type of biologic medicine that has been developed to be highly similar and clinically equivalent to an existing approved biologic (referred to as a ‘reference medicine’ or ‘originator medicine’) in terms of structure, biological activity, immunogenicity, quality, safety and efficacy. They are in great demand and are quickly becoming the standard of care in clinical trials due to their safety, efficacy and competitive pricing. Latest information can be found on the European Medicines Agency (EMA) website. As with any biologic medicine, details of biosimilars’ licensed indications are included in the British National Formulary (BNF). It is important to note that biosimilars are not considered generics of biologic medicines. This is due to the small degree of variability (‘microheterogeneity’) that naturally exists in the complex structure of the active substance within and between batches. To ensure the consistency and quality of all biological medicines, including biosimilars, UK and EU legislation upholds strict requirements. Learn more about key regulatory considerations on CSI’s blog Biosimilars FAQ When purchasing biosimilars for use in clinical trials, the following questions are often raised: Is the biosimilar licensed for all the indications and routes of administration required? 1 Is the biosimilar available in suitable strengths and presentations? 2 Is the administration device acceptable to the patient and are product-associated support services available? 3 CSI’s scientific knowledge and experience of supplying biologics and biosimilar medicinal products to complex global studies means we are perfectly placed to navigate these questions and help our partners to deliver successful trials. Learn more about key regulatory considerations on CSI’s blog Biologics and biosimilars that CSI has extensive experience in supplying globally Adalimumab Bevacizumab Cetuximab Aflibercept Daratumumab Trastuzumab Trastuzumab Adalimumab Adalimumab Ruxolitinib Pembrolizumab Ranibizumab Rituximab Bevacizumab Nivolumab Infliximab Ustekinumab Atezolizumab Rituximab Ipilimumab Adalimumab Filgrastim Pegfilgrastim Contact us Get in touch with a member of our experienced team today to discuss your clinical trial supply requirements Company type Submit

Global comparator drug sourcing with 25+ years of expertise. Tailored procurement strategies and extensive network ensure reliable, on-time delivery of hard-to-find medicines for clinical trials. We provide world-leading, bespoke clinical trial supply chain solutions focusing on comparator sourcing At CSI, we take a scientific approach to comparator sourcing based on our 150 years of experience in the clinical trial supply industry. Comparators are on the critical path of almost all clinical studies but are increasingly expensive and hard to find. We pride ourselves on finding the unfindable, sourcing comparator drugs that allow clinical trials to run on time and provide better patient outcomes. Comparator Drug Sourcing The clinical supply partner of choice Pharmaceutical companies , biotechnology companies and Clinical Research Organisations (CROs) must have robust comparator sourcing strategies in place to ensure that comparator drugs are supplied to all clinical trial sites at a competitive price and without disruption. CSI has supplied medicines to over 1,200 clinical trials across lifecycle phases 1 to 4, supporting our partners with even the most complex and challenging requirements. We understand that every clinical study is different and requires a customised approach. With the experience to take on even the most complex adaptive trials, we know how to reduce complexity and drive value, delivering sourcing strategies to improve the speed and agility of your study. CSI delivers results with: A comprehensive understanding of clinical trial requirements and protocols Fully bespoke sourcing solutions, whether country-specific, global or hybrid A global network of qualified suppliers, manufacturers and wholesalers A wide range of suppliers to minimise risks and enable sourcing of specific batches Full documentation, client support and supply chain transparency CSI’s six drivers of effective comparator sourcing Understanding the science behind a clinical trial informs CSI’s efficient supply strategies Protocol interpretation Protocol interpretation Product access Product access Supply continuity Supply continuity Cost control Cost control Speed Speed Supporting documents Supporting documents Our most frequently supplied comparator medicines Humira adalimumab Arthritis Eylea aflibercept Ophthalmology Tecentriq atezolizumab Oncology Bavencio avelumab Oncology Avastin bevacizumab Oncology Yervoy ipilimumab Oncology Abraxane nab-paclitaxel Oncology Opdivo nivolumab Oncology Ibrance palbociclib Oncology Keytruda pembrolizumab Oncology Lucentis ranibizumab Ophthalmology Stivarga regorafenib Oncology Mabthera rituximab Oncology Jakavi ruxolitinib Oncology Talzenna talazoparib Oncology Roactemra tocilizumab Arthritis Branded Name Scientific Name Indication Overcoming the challenges of comparator drug sourcing The sourcing of comparator drugs and non-investigational medicinal products (NMPs) has become increasingly critical as most drugs are now tested against the standard of existing care. Despite market growth and development, it is becoming more difficult to guarantee the timely availability of comparator drugs due to many of the products being biologic medicines , which are difficult to produce and distribute. Working with CSI will streamline your clinical trial supply chain and ensure high-quality comparator drugs are sourced in a timely and cost-effective manner. Our scientific expertise means we can advise on new investigative drugs and, with our global reach and emphasis on quality , you can always rely on us to deliver. Case Studies Oncology Products Biosimilars Oncology Products CSI specialises in supplying oncology products to global clinical trials. We have successfully delivered oncology products to more than 1000 studies, from generics to the most sophisticated cold chain biologics Discover more Biosimilars CSI has extensive experience of supplying biosimilar medicines to a wide range of clinical trials, including the navigation of strict government regulations around the world. Our strong relationships with leading manufacturers and our global network of trusted suppliers make us the ideal supply partner for biosimilars. Discover more Comedications The standard of care for many indications, especially in oncology, is now a combination of drugs that together provide maximum efficacy. Comedications may be used to alleviate side effects or to improve the potency of the treatment. Comedications are common in cancer treatment because of the multitude of biological mechanisms at play in disease progression. Combination therapies play a crucial role in the comprehensive care of patients, from managing risks to creating synergies that give the gold-standard of treatment. Critically, for clinical trials, the increasing prevalence of combination therapies being used as comparators means more complexity and greater risk from delays, drug shortages, disruptions and compromised supply chains. Securing multiple products on time, and in the right condition, is even harder when each requires a different supplier and logistics solution. CSI has the expertise and experience to help our partners to overcome these challenges. Our scientifically-minded team has the knowledge to advise on the optimal sourcing strategy for all comedications and combination therapies that might be required for any trial, factoring in origin of supply, price, logistics and shipment timing. Rescue Studies We apply our same expertise, global footprint and operational excellence in service of global studies that may need rescuing, whether this relates to issues of procurement, sourcing, resource, compliance, quality or timelines. With CSI’s decades of experience in the clinical trial supply industry and dedicated client relationship managers, we are here to help you get your study back on track. CSI has sourced rescue medications for a range of global studies, including the supply of salbutamol, Remicade (infliximab), Jakavi (ruxolitinib) and mycophenolate motefil. Case Study

CSI is the global science-based clinical trial supply expert with over 25 years of experience in comparator sourcing. Your trial benefits from our solutions. Your trial. Our solutions. The trusted global leader in the supply of comparator drugs, medical devices, and ancillaries for clinical trials WHAT WE DO Your trial. Our solutions. We are CSI Bringing science to clinical trial supply Our team’s scientific experience and global project management expertise enable us to deliver tailor-made solutions to support your study ABOUT US We have never failed to deliver to a study Clinical trials supplied 1,200+ Suppliers and manufacturers 200+ Years of global experience 150+ Our Services We manage the entire clinical supply chain Medicines and Ancillaries Storage and Distribution Project Management Global expertise with unrivalled local knowledge Read more Depot network across six continents Direct-to-site or warehouse delivery Shelf-life control Cold chain management Secure shipment tracking Returns, reconciliation and destruction Qualified Person, regulatory services and independent quality department A scientific approach to clinical trial supply Read more Protocol analysis Exploring and mapping opportunities and solutions Budgeting and forecasting Supply planning and management Risk evaluation for potential shortages and price fluctuation Global market trends and analysis We pride ourselves on finding the unfindable Read more Biosimilars Rescue studies Medicines and comparator sourcing Oncology products Reference samples for analysis Medical devices Ancillaries Specific lots or batches Case Study Oncology Trial Supplying a leading Biotech’s global Phase 3 study Challenge To supply a Phase 3 high value oncology product trial spanning 14 countries within eight weeks and to ensure regular resupply for three years Solution CSI’s manufacturer relationships and depot network ensured high volumes of ruxolitinib were sourced and delivered on time Result Efficient supply of the product allowed scheduled Site Initiation Visits (SIVs) to take place, keeping the Biotech’s study on track More Case Studies Our Expertise Six areas in which CSI excels With offices around the world and warehouses in 60 countries, we are equipped to provide solutions to the most complex clinical supply requirements Locations A truly global footprint With decades of combined experience in the field of drug development, we understand the successful design and execution of clinical trial supply Leadership Experienced leadership We are proud to be the trusted global partner of leading pharmaceutical and biotechnology companies, and Clinical Research Organisations (CROs) Our Partners Building lasting relationships We have supplied oncology products to more than 700 studies, from generics to the most sophisticated cold chain biologics Oncology Products Oncology specialists CSI is committed to improving trial success rates, patient safety and the progress of medicine. We are proud to be Women Owned and EcoVadis certified Our Values A positive impact As a reliable global partner, our comprehensive knowledge of international regulations and compliance lies at the heart of all the services we provide Quality Quality you can trust North America Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt. Canada Guatemala Mexico Panama United States EMEA Austria Belgium Bulgaria Croatia Czech Republic Denmark Egypt Estonia Finland France Germany Greece Hungary Ireland Israel Italy Jordan Latvia Lebanon Lithuania Netherlands Norway Oman Poland Portugal Romania Russia Saudi Arabia Serbia Slovakia Slovenia South Africa Spain Sweden Switzerland Tunisia Turkey United Arab Emirates United Kingdom South America Argentina Brazil Colombia Peru Asia Pacific Australia China India Japan Malaysia Philippines Singapore South Korea Taiwan Thailand Vietnam Global Reach Warehouses Offices CSI's sourcing capabilities are served by an extensive network of audited manufacturers and suppliers, strategically positioned across 60 countries on six continents Our Global Reach Warehouses and offices Our network extends to 60 countries on six continents Our Partners Why work with us? Pharmaceutical and Biotechnology Companies CSI is a proud supplier to top-ten pharmaceutical companies and leading biotechs around the world, providing tailor-made solutions and country-specific regulatory expertise to boost success rates for even the most complex global trials Discover more Clinical Research Organisations (CROs) Along with our smart sourcing solutions and unrivalled product access, we manage the entire supply chain, allowing CROs to concentrate on finding patients and delivering successful clinical trials – saving time, money and resources Discover more Hospitals and Academic Institutions CSI works closely with world-class academic institutions, universities, hospitals and research centres that are producing cutting-edge medical research, supporting them by providing cost-effective and compliant clinical trial supplies Discover more News & Updates Insights Read all News Read all Events Read all Case Studies Read all Latest News Read all Featured Read all Navigating Trump-Era Tariffs Read all CSI’s Strategic Approach to Mitigating Clinical Trial Supply Disruption Recent developments in U.S. trade policy are shaking up supply... Clinical Services International (CSI) Insights News & Updates 25/04/25 CSI are Qualified with SAM.gov and BARDA Read all We’re proud to share that CSI is now fully registered and qualified with SAM.gov and BARDA , enabling us to support U.S.... Clinical Services International (CSI) News News & Updates 09/04/25 Choose CSI as your supply chain partner Read all Clinical Services International (CSI) Featured News & Updates 20/12/24 CSI's Life Sciences Review Read all CSI is excited to have our Managing Director Vanessa Dekou featured on the front cover of Life Sciences Magazine! This recognition is... Clinical Services International (CSI) Latest News News & Updates 09/10/24 CSI are speaking at COG Europe Read all CSI are presenting at the Clinical Outsourcing Group (COG) Conference in Amsterdam on 12th-13th November. As the leader in clinical... Clinical Services International (CSI) Events News & Updates 25/09/24 Attend CSI's presentation at CTS East Coast! Read all CSI are attending and presenting at Clinical Trial Supply (CTS) East Coast! Vanessa Dekou PhD, MBA will be speaking at 12:30pm, Stream... Clinical Services International (CSI) Events News & Updates 25/09/24 CSI is exhibiting at OCT New England! Read all CSI is exhibiting at Outsourcing in Clinical Trials (OCT) New England! Our Executive Vice President Jean Bowtell and Designated... Clinical Services International (CSI) Events News & Updates 25/09/24 Visit CSI at GCSG in Malta! Read all CSI is attending GCSG Europe, in Malta on the 15-17th October, the leading industry meeting where people get together to share knowledge... Clinical Services International (CSI) Events News & Updates 25/09/24 Are you attending Expopharm? Read all CSI's Managing Director Vanessa Dekou PhD, MBA and Project Manager Aylin Asadian will be attending on the 9th October to discuss... Clinical Services International (CSI) Events News & Updates 25/09/24 CSI Partners with Ryvu Read all Ryvu Therapeutics Announces Entering into Agreement with Clinical Services International (CSI) in the Area of Securing Venetoclax Supply... Clinical Services International (CSI) News News & Updates 31/07/23 Diabetes Awareness Read all Diabetes Week (12–18 June 2023), set up by the British charity group Diabetes UK, provides a special opportunity and focal point to... Clinical Services International (CSI) Events News & Updates 03/07/23 How to overcome drug shortages in the clinical trial supply chain Read all Learn about CSI’s expert risk management strategies One of the biggest challenges faced by clinical trial supply management companies are... Clinical Services International (CSI) Insights News & Updates 14/06/23