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More case studies

Export of expensive comparators from Europe to China with first leg documents and streamlined approach

CSI’s seamless comparator export to China

CSI’s flexible approach to global distribution ensured a large CRO's five-year and three-year studies across a total of 18 countries could proceed without delay

Global Device Distribution

How CSI rescued an oncology trial when a competitor failed to deliver, despite an extremely tight deadline and scarce supply on the market

Rescuing a Global Biotech's Oncology Study with Cetuximab

How CSI supplied large quantities of ruxolitinib to a CRO’s ongoing Phase 3 oncology study involving 14 countries, nine depots and 67 site shipments

Global CRO Oncology Partnership

How the flexibility and initiative of CSI’s Quality team overcame challenges to ensure timely product supply for a partner’s ongoing clinical trial

A Quality Solution to Clinical Trial Supply

How CSI delivered mission impossible: sourcing specific tested batches of an expensive oncology product from several European markets

Oncology Product Batch Hunting

How CSI used its scientific expertise at the protocol stage to provide flexibility in sourcing strategy and ensure high volumes of a single product were supplied on time to multiple countries

Delivering Comparators for a Global Allergy Study

How CSI’s regulatory guidance and robust sourcing solutions ensured the success of a global flu vaccine trial that could not afford to run behind schedule

Sourcing Flu Vaccines for a Global Trial

How CSI leveraged its vendor and warehouse networks to supply aflibercept for a leading CRO’s oncology study within a tight deadline

Rapid Oncology Study Supply

How CSI’s scientific insight delivered an agile sourcing model and substantial cost savings for a listed biotechnology company’s global trial

Streamlining Biotechnology Supply Chains

How CSI leveraged relationships with multiple manufacturers to urgently supply large quantities of a generic drug to a global Phase 3 trial

Overcoming Drug Shortages


Pembrolizumab is a type of immunotherapy used for the treatment of a wide variety of cancers, including non-small cell lung cancer, melanoma and classical Hodgkin lymphoma. It is one of the most sought-after medicines for use as a comparator in clinical trials. Because of this, the manufacturer makes sourcing the product challenging and commands a very high premium for its use in clinical trials compared to the wholesale price of the product in most European markets. Our client, a leading global pharmaceutical company, required considerable volumes of the product for their clients’ trials and came to CSI for a cost-effective sourcing solution.


CSI identified reliable suppliers that could offer the product in significant volumes with all the relevant documents available and no trial disclosure required, and all at a price significantly lower than that offered to our client by the manufacturer: a 30% reduction when all supporting documentation was required, and 40% when Certificates of Analysis (CoA) were not mandatory.


CSI has been delivering pembrolizumab (sourced at 30–40% lower than the manufacturer’s price) consistently to our pharmaceutical company client for the past couple of years, fulfilling seven purchase orders on time and, in the process, delivering a saving in the region of €1 million.

Case Study

Delivering €1 million Savings for Pembrolizumab

How CSI has saved a leading global pharmaceutical company €1 million by sourcing pembrolizumab from the market at the best possible price


To source large quantities of an expensive oncology drug for a pharmaceutical company at a price much lower than that offered by the manufacturer


CSI leveraged its network of reliable suppliers to present sourcing options to the client that demonstrated a considerable discount


Our client has been supplied with pembrolizumab consistently for the past couple of years, saving €1 million thanks to CSI’s sourcing solutions

Get in touch with a member of our experienced team today to discuss your clinical trial supply requirements

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